A growing number of patients who experience persistent joint pain and inflammation may be living with undiagnosed autoimmune arthritis—even when their standard blood tests return normal results.
Many individuals are reassured that “everything is normal,” yet they continue to suffer. Unfortunately, some patients only reach a specialist after irreversible joint damage has already occurred.
When Blood Tests Don’t Tell the Full Story
Approximately 10% or more of autoimmune arthritis cases may not be detectable through standard laboratory tests.
In some patients, the condition may even affect major organs such as the kidneys, lungs, or liver. Because laboratory markers can appear normal, early signs may be overlooked or misinterpreted—delaying diagnosis and treatment
Why Clinical Evaluation Matters
A thorough clinical assessment is essential when symptoms persist despite normal results.
Subtle clues in a patient’s medical history, physical examination, and—when appropriate—imaging studies may indicate an autoimmune condition even in the absence of abnormal laboratory findings.
In some cases, misinterpretation of lab or imaging results can further prolong diagnosis. This reinforces the need for expert evaluation by a rheumatology specialist.
The Importance of Early Specialist Consultation
Timely diagnosis and early treatment play a key role in preventing long-term joint damage and improving patient outcomes.
If joint pain, stiffness, or swelling does not resolve—or keeps returning—seeking specialist advice can help identify underlying autoimmune inflammation before it leads to irreversible complications.
Dr. Bassel Darwish is a Consultant Rheumatologist based in Dubai, UAE.
He is certified by the American Board of Internal Medicine in Rheumatology and is recognized for his expertise in autoimmune diseases, inflammatory arthritis, and complex multisystem conditions.
