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Rheumatology

Rheumatic Diseases and Fatigue — Video

Dr. Bassel DarwishOctober 21, 20262 min read
Written and medically reviewed by Dr. Bassel Darwish — Consultant Rheumatologist · Last updated October 21, 2026

A one-minute animated explainer on why people with rheumatic diseases may feel fatigued, which other causes are worth considering, and how a clinician decides whether tests are needed.

For the full guide, including vitamin and mineral deficiencies, assessment and frequently asked questions, read Dr. Bassel Darwish’s article Can Rheumatic Diseases Cause Fatigue?.

Video transcript

Fatigue can be more than tiredness. It may affect work and daily life.

Rheumatic diseases like rheumatoid arthritis, lupus, and Sjogren's can cause fatigue through inflammation even when joint pain is mild. Pain, stiffness, poor sleep, anemia, medication effects, reduced activity, stress, and low mood may contribute.

But fatigue has many causes, and alone it does not prove autoimmune disease or a flare. Thyroid disease, diabetes, infection, sleep disorders, and other conditions may play a role.

A clinician considers your symptoms, sleep, medicines, and examination to decide whether tests are needed. No single test explains fatigue in everyone.

With a rheumatic condition, new fatigue may prompt review of disease activity and other causes. Fatigue alone does not mean treatment should change. A careful assessment can guide the next step.

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Written by Dr Bassel Darwish

Consultant Rheumatologist

Credentials & training

  • American Board of Internal Medicine (ABIM) certification logo

    ABIM Board Certified — Internal Medicine · Rheumatology

  • American College of Rheumatology (FACR) fellowship badge

    Fellow, American College of Rheumatology (FACR)

  • University of Wisconsin–Madison logo

    Rheumatology Fellowship, 1997–1999 — University of Wisconsin School of Medicine and Public Health

View Dr Bassel Darwish’s full profile →

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